Abstract

Background

Frequent binge drinking is a known contributor to alcohol-related harm, but its impact on systemic and hepatic inflammation is not fully understood. We hypothesize that changes in immune markers play a central role in adverse effects of acute alcohol intake, especially in patients with early liver disease.

Aim

To investigate the effects of acute alcohol intoxication on inflammation-related markers in hepatic and systemic venous plasma in people with alcohol-related liver disease (ArLD), non-alcoholic fatty liver disease (NAFLD) and healthy controls.

Methods

Thirty...

In this bulletin, data on treated problem alcohol use for the year 2022 are presented, followed by trends for the seven-year period from 2016 to 2022.

The data are from the National Drug Treatment Reporting System (NDTRS), the national surveillance system that records and reports on cases of drug and alcohol treatment in Ireland.

Included in the NDTRS are cases treated in all types of services: outpatient, inpatient, low threshold, general practitioners (GPs), and those treated in prison.

This briefing provides a summary of alcohol consumption, alcohol harm, alcohol treatment, and gaps in knowledge regarding alcohol use among LGBTQ+ people.

It uses the acronym LGBTQ+ to include lesbian, gay, bisexual, transgender, queer, questioning, and ace people (as defined by Stonewall), which encompasses both sexual or romantic orientation and gender identity.

The briefing includes information on alcohol consumption, alcohol-related harm and alcohol treatment.

24 مئی 2023 کو زوم پر منعقد ہونے والے ایس اے اے پی / ایس اے آر این 'الکوحل کبھی کبھار' ویبینار کی ویڈیو دیکھیں: "ایل جی بی ٹی کیو + لوگوں کے لئے شراب کی مارکیٹنگ: شناخت کو ہدف بنانے کے لئے حکمت عملی تیار کرنا"، ڈاکٹر ڈیوڈ وائٹلی.

INTRODUCTION: The study protocol is focused on qualitative and quantitative analysis and reflection of the media image and presentation of direct and hidden alcohol advertising in the Czech mass media, with an emphasis on social network platforms with a high degree of influence on young people. It responds to the need for verified resource points for discussion of the effectiveness and extent of the existing statutory regulation of alcoholic beverage advertising and methods for its possible tightening.

METHODS: For the analysis of traditional (printed) media, the method of content analysis...

BACKGROUND: Tobacco smoking and alcohol consumption are widespread practices that are legal and socially accepted in many societies. One of the common tools to reduce the consumption of these legal drugs is increasing prices. The prices for customers include taxes (value added tax and excise tax). Hundreds of studies from around the world are interested in the impact of taxes and prices on the demand for tobacco products. This topic is also relevant for governments of all countries trying to regulate consumption.

AIM: The aim of the paper is to describe the amount of excise tax on legal drugs...

Canada’s Guidance on Alcohol and Health provides evidence-based advice on alcohol to support people in making informed decisions about their health. The guidance is based on the latest research on alcohol-related risks and replaces Canada’s Low-Risk Alcohol Drinking Guidelines.

The guidance is based on the principle of autonomy in harm reduction and the fundamental idea behind it that people living in Canada have a right to know that all alcohol use comes with risk.

Key points from the guidance include:

• There is a continuum of risk associated with weekly alcohol use where the risk of harm...