This report examines how the rapid growth of synthetic drug markets is transforming the global drug landscape and challenging traditional approaches to drug control. Unlike plant-based drugs such as cocaine and heroin, synthetic drugs can be manufactured almost anywhere using a wide range of precursor chemicals, making production more flexible and difficult to disrupt.

The report highlights that synthetic drug markets are now present in almost every country and have experienced the fastest growth of any criminal market since 2021. Lower barriers to production have enabled both organised...

This threat assessment examines the potential risks posed by highly potent synthetic opioids (HPSOs) in Europe over the next two years. Drawing on early warning data, forensic and clinical evidence, and expert input, the report explores how opioid-related harms could develop under different scenarios and identifies key uncertainties that may influence future trends.

The assessment highlights the emergence of these substances as a significant public health and security concern due to their extreme potency, the risk of overdose at very low doses, and their presence in counterfeit or...

The UNODC World Drug Report 2026 introduces a new interactive platform that allows users to explore the latest global, regional, and subregional trends in drug demand and supply through dynamic data visualisations, maps, graphs, and downloadable datasets.

 

The Drug Market Patterns and Trends platform presents concise, evidence-based analyses across a range of topics, enabling users to examine emerging developments in drug markets, patterns of use, production, trafficking, and related indicators. Each finding is supported by interactive visualisations, with the underlying data available for...

This report examines how and why young people are recruited into criminal drug networks across Europe. It highlights the range of factors that can increase vulnerability to recruitment, including social and economic disadvantage, peer influence, family circumstances, and community environments.

Drawing on international evidence, the report identifies several promising approaches to prevention, including family-based support, school-based interventions, community engagement, digital prevention initiatives, and targeted efforts to disrupt criminal networks. It also emphasizes the importance of...

The European Union Drugs Agency (EUDA) continues to monitor illicit drug production and precursor chemicals across Europe to improve understanding of how drug markets are evolving. Production within the European Union is primarily focused on synthetic stimulants, including amphetamine, MDMA, methamphetamine, and synthetic cathinones, while production methods are becoming increasingly flexible and adaptive.

The report also highlights the significant environmental and public safety risks associated with illicit drug production. Drug manufacturing can generate large amounts of hazardous chemical...

The European Drug Report 2026: Trends and Developments provides the latest overview of the drug situation across Europe, drawing on data from EU Member States, Türkiye, and Norway. The report examines patterns of drug use, drug-related harms, drug supply, treatment services, and other interventions, offering a comprehensive picture of developments up to the end of 2025.

Using data collected through national monitoring systems and European research networks, the report highlights emerging trends and supports evidence-informed responses to drug-related challenges. It also emphasises the...

The UN Toolkit on Synthetic Drugs is a practical online resource coordinated by UNODC that brings together tools, guidance, and operational resources from across the UN system to support responses to the global synthetic drug problem. Covering topics such as diversion prevention, investigations, trafficking, criminal financing, and cybercrime, the Toolkit is regularly updated to help policymakers, law enforcement agencies, and practitioners address the rapidly evolving synthetic drug landscape.

 

ISSUP will be sharing selected modules, tools, and resources from the UN Toolkit on Synthetic...

The Tobacco Control Scale 2025 shows that progress in tobacco control across Europe has slowed, with more countries recording lower scores than in previous years. Key reasons include the failure to regulate heated tobacco products in the same way as cigarettes and the lack of adjustments to tobacco taxes and prices to keep pace with inflation.

This European guide by EUDA highlights the importance of addressing dual disorders, where mental health conditions and substance use disorders occur at the same time. These co-occurring conditions are common and often lead to poorer health outcomes, increased social marginalisation, and more complex recovery pathways.

The guide emphasizes that effective responses require integrated and coordinated care, bringing together mental health services, addiction treatment, medication management, and social support. It also highlights the value of early identification, personalised treatment plans...

UNODC has launched a new Security Document Examination module within the UN Toolkit on Synthetic Drugs, developed in collaboration with the UNODC Laboratory and Scientific Services. The module aims to help law enforcement, border control authorities, and forensic experts detect and respond to the use of fraudulent documents in synthetic drug trafficking.

Criminal networks often rely on forged passports, identity documents, and manipulated shipping and travel records to conceal identities and facilitate cross-border operations. The new module provides practical guidance on document examination...

The European Union Drugs Agency has released updated data sheets providing a clear and comparable overview of drug-related indicators across six Western Balkan partners under the Instrument for Pre-accession Assistance (IPA). These include Albania, Bosnia and Herzegovina, North Macedonia, Kosovo, Montenegro, and Serbia.

The data sheets bring together health and security information in one place, making it easier for policymakers and practitioners to access and use routine data. They are part of ongoing EU support to help these countries strengthen monitoring systems and align with EU...

The European Commission has introduced new controls on nine high-risk chemical precursors used in illicit drug production under Delegated Regulation (EU) 2026/314. Most of these substances are linked to synthetic cathinones, while one is used in amphetamine production.

This measure responds to the growing scale of synthetic drug production in Europe, with dozens of production sites dismantled in recent years. The regulation is based on updated risk assessments that improve understanding of how precursor chemicals are sourced and diverted into illegal markets.

Overall, the new controls aim to...

Drug trafficking in the Pacific is rapidly expanding, shifting countries from transit points to consumer and production markets. However, many national laws remain outdated, as they were designed for earlier challenges like cannabis and are not equipped to address synthetic drugs and cocaine.

Governments are under pressure to respond, leading in some cases to tougher punitive proposals, but legislative reform alone is not keeping pace with the evolving threat. Fiji’s recent approach shows a more integrated model, combining law enforcement, public health, and community engagement through broad...

The 2025 Global Organized Crime Index shows that overall crime levels in Europe remain stable, and the region continues to rank among the least affected globally. However, this stability hides a more complex reality, with criminal markets and actors evolving and expanding.

Financial crime is the most widespread threat, driven by online fraud and cross-border schemes, while cybercrime continues to grow, often linked to state-backed or hybrid actors. Drug markets are also shifting, with cocaine and synthetic drugs increasing, while trafficking and smuggling networks remain deeply entrenched.

A...

Short Summary

Scam centres are a fast-growing global organized crime threat, generating over $1 trillion in losses in 2024. They use technology and psychological manipulation to target victims worldwide, supported by global criminal networks and easy-to-access tools.

Despite enforcement efforts, scams are expanding and adapting, often moving to low-governance environments and exploiting geopolitical gaps.

Key Actions

• Increase international coordination and intelligence sharing

• Pressure safe havens and strengthen regulation of tech and financial platforms

• Cooperate across...