Background
A non-medicalized safer supply model called a “Compassion Club” has recently been evaluated. The model involved providing rigorously tested and accurately labeled illicit substances to members at cost. Operating for 14 months in Vancouver's Downtown Eastside, the initiative aimed to explore the effects and feasibility of this approach among individuals at risk of fatal overdose.

Methods
At the one-year mark, 43 club members completed a survey for this cross-sectional analysis. Descriptive statistics were used to assess the perceived impact of membership on factors like drug use...

Addiction and obesity share similar neurological pathways, both linked to compulsive behaviors and the brain's reward system. Research has highlighted the potential of GLP-1 receptor agonists, originally developed for diabetes, to help manage both appetite and addictive cravings. These medications, such as semaglutide, may regulate addictive behaviors by influencing reward circuits in the brain. However, they come with potential side effects, and their long-term effects are still under investigation.

In addition, a new compound, 5-Methoxy-2-aminoindane (MEAI), is being researched for its...

Visually presents substance use trends and describes whether expected substance use aligned with actual substance contents. Data were collected from harm reduction sites in seven regions across Canada that participated in the Community Urinalysis and Self-Report Project between 2021 and 2023.

Drugs from the unregulated market often contain added substances that people who use drugs do not know are there or do not intend to use. This is a key driver of unintentional drug poisoning and the drug poisoning crisis.

SAMHSA report discusses the evidence supporting the effectiveness of screening, brief intervention, and referral to treatment (SBIRT) as a comprehensive approach, as well as for the implementation and effectiveness of the individual components of SBIRT for different behavioural health conditions.

The report describes briefly the underlying research that has been conducted in the prevention and early intervention of risky alcohol, substance abuse and tobacco consumption, as well as commonly reported mental health problems, and describes existing studies/models for specific populations and...

The ASSIST package, which consists of a brief questionnaire, a guide for health professionals on how to use the questionnaire in detecting and responding to substance use and also a self-help manual for cutting down or stopping substance use, is the result of more than 10-years work by WHO and an international group of researchers in the framework of the WHO ASSIST project. It is WHO’s response to the growing demand for guidance on how to best manage problems of substance use in non specialist health care settings. This approach, quick and easy to learn, useful for all substances including...

The DIMS annual report 2022 covers the concentrations, adulterations, and other relevant information produced by DIMS in the past year, and in doing so forms a topical image of the Dutch drug market. Spread out over all Dutch provinces, the DIMS network encompasses 32 testing-facilities providing nation-wide coverage. Together with these partners, DIMS aims to create a clear insight into the Dutch drug market, and signal potential health risks to the public.

La cocaína es una droga estimulante adictiva que se origina en las hojas de la planta de coca, que es autóctona de América del Sur. Los efectos de la droga incluyen un mayor estado de alerta, atención y energía, así como sentimientos de euforia y confianza. Sin embargo, estos efectos tienen un alto costo, ya que el consumo de cocaína puede llevar a una serie de consecuencias negativas para la salud y sociales.

También puede visitar la Red ISSUP sobre cocaína, para acceder a más recursos. El cuarto folleto se centra en el mercado mundial de estimulantes, incluida la cocaína. 

1) El Informe...

Puntos clave

Pregunta  : ¿Qué tratamientos para el trastorno por consumo de cocaína se asocian con reducciones objetivas en el consumo de cocaína entre los adultos?

Hallazgos  En este metaanálisis de 157 ensayos clínicos que comprendieron 402 grupos de tratamiento y 15 842 participantes, solo los programas de manejo de contingencias se asociaron significativamente con una mayor probabilidad de tener un resultado negativo en la prueba para la presencia de cocaína, y esta asociación siguió siendo significativa en todos los análisis de sensibilidad. 

El manejo de contingencias (MC) es un tipo...

Visión general

La cocaína es la sal clorhidrato producida a partir de las hojas de la planta de coca. La cocaína en polvo generalmente se inhala y se inyecta con menos frecuencia. El crack es una forma fumable de cocaína y se fabrica a partir de clorhidrato de cocaína.

La cocaína es conocida por sus efectos inmediatos y su asociación con patrones problemáticos de consumo de drogas. 

En esta página puede encontrar enlaces a datos, publicaciones científicas y recursos disponibles del OEDT sobre el tema de la cocaína y la cocaína crack.

Los recursos están disponibles en las siguientes...

The cocaine market presents a clear threat at the global level. Well-defined locations of production in South America and large consumer markets in the Americas and Europe lead to trafficking routes from a circumscribed origin to specific, even if far-flung, destinations. While some parts of the world play a crucial role as transit regions, the routes, modalities, and networks employed by criminal actors continue to evolve, diversify and become more efficient. The increasingly globalized, interconnected, digitalized and technologically sophisticated nature of society, as well as a growing...

En el contexto de una expansión continua del mercado mundial de cocaína, este informe resume el estado actual del conocimiento sobre qué son los productos de consumo de cocaína y cómo se producen y consumen en diferentes regiones del mundo. El informe se basa en la evidencia publicada disponible y en el conocimiento adquirido a través de las actividades de monitoreo de UNODC en los países de América del Sur.

Ofrece información sobre el espectro de productos de cocaína para ayudar a los profesionales en la oferta de drogas y la reducción de la demanda de drogas, como las agencias de aplicación...