Supply & Market Disruption

Supply and market disruption refers to coordinated strategies aimed at reducing the production, trafficking, distribution, and availability of illicit substances. These strategies often involve law enforcement, regulatory controls, border management, and financial investigations designed to disrupt drug trafficking networks and weaken illicit drug markets. By targeting supply chains and market dynamics, these efforts aim to reduce the availability of drugs, increase the risks and costs associated with illegal production and distribution, and contribute to broader efforts to reduce substance-related harms. Effective supply and market disruption typically operates alongside public health, prevention, treatment, and recovery responses as part of a comprehensive approach to substance use. 

Drug production and precursors — EUDA ongoing activities

Website
The European Union Drugs Agency (EUDA) continues to monitor illicit drug production and precursor chemicals across Europe to improve understanding of how drug markets are evolving. Production within the European Union is primarily focused...
EUDA

2025 National Drug Threat Assessment (NDTA) - Drug Enforcement Administration (DEA)

Report
The U.S. Drug Enforcement Administration (DEA) has released its 2025 National Drug Threat Assessment (NDTA), providing an overview of the threats posed by illicit drugs and the transnational criminal organizations involved in their production and trafficking. The report highlights the continuing impact of synthetic drugs, particularly fentanyl and methamphetamine, on public health, public safety, and national security.
The Drug Enforcement Administration (DEA)

UN Toolkit on Synthetic Drugs

Toolkit
The UN Toolkit on Synthetic Drugs is a practical online resource coordinated by UNODC that brings together tools, guidance, and operational resources from across the UN system to support responses to the global synthetic drug problem...

New UNODC Toolkit Module on Security Document Examination: Launching event

Event Date
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Online
- Global -
Attendance
online

UNODC has launched a new Security Document Examination module within the UN Toolkit on Synthetic Drugs to help law enforcement, border control, and forensic professionals detect and respond to document fraud linked to synthetic drug trafficking.

UNODC Current NPS Threats

Report
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The UNODC Early Warning Advisory highlights a continued global expansion of new psychoactive substances (NPS), with nearly 1,400 substances reported worldwide. In 2024 alone, a record number of substances were identified, including over 100...
UNOPS

EU controls nine drug precursors following first EUDA assessments

News
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The European Commission has introduced new controls on nine high-risk chemical precursors used in illicit drug production under Delegated Regulation (EU) 2026/314. Most of these substances are linked to synthetic cathinones, while one is...
EUDA News