Applying interventions designed to reduce and manage the symptoms of substance use disorders.
Treatment
8 Steps Towards Minimising the US Opioid Crisis
Current levels of opioid addiction in the US are so alarming that in July 2017 the President’s Commission on Combating Drug Addiction and the Opioid Crisis urgently suggested that President Trump declare a national emergency to free up...

Drug and Alcohol Treatment Statistics
Executive Summary Data collected in drug treatment agencies play a prominent role in informing policy makers. Such data often represent the only information collected regularly and consistently over a certain period of time. What is even...

Effectiveness Bank Drug Treatment Matrix Cell C1: Life and Death Decisions for Drug Harm Reduction Management
Explores how harm reduction impacts are affected by the management of the service and of the intervention. Highlights the studies which showed that treatment-termination and needle-exchange policies can mean life or death for service users...
Brief Intervention to Promote Smoking Cessation and Improve Glycemic Control in Smokers with Type 2 Diabetes
Abstract The aim of the study was to examine the effects of a brief stage-matched smoking cessation intervention group compared with a control group (with usual care) in type 2 diabetes mellitus patients who smoked by randomized controlled...
Effectiveness of Optional Videoconferencing-Based Treatment of Alcohol Use Disorders
ABSTRACT Background: Treatment of alcohol use disorders (AUDs) is characterized by an adherence rate below 50%. Clinical research has found that patient adherence enhances treatment effect; hence, health authorities, clinicians, and...
Transcranial Magnetic Stimulation of Dorsolateral Prefrontal Cortex Reduces Cocaine Use
Abstract Recent animal studies demonstrate that compulsive cocaine seeking strongly reduces prelimbic frontal cortex activity, while optogenetic stimulation of this brain area significantly inhibits compulsive cocaine seeking, providing a...
Efficacy and Safety of High-Dose Baclofen for the Treatment of Alcohol Dependence
Abstract Previous randomised placebo-controlled trials with low-to-medium doses of baclofen (30–60 mg) showed inconsistent results, but case studies suggested a dose-response effect and positive outcomes in patients on high doses of...
Effectiveness Bank Drug Treatment Matrix Cell B1: The Practitioner in Harm Reduction
Second cell of the Drug Treatment Matrix explores key studies on the impact of the practitioner on reducing harms associated with illegal drug use, in which trust emerges as a fundamental ingredient. Reconceptualise needle exchanges as safe...
Multimorbidity in Patients Enrolled in a Community-Based Methadone Maintenance Treatment Programme Delivered through Primary Care
Abstract Background: Multimorbidity, the co-existence of two or more (2+) long-term conditions in an individual, is common among problem drug abusers. Objective: To delineate the patterns, multimorbidity prevalence, and disease severity in...