Recent animal studies demonstrate that compulsive cocaine seeking strongly reduces prelimbic frontal cortex activity, while optogenetic stimulation of this brain area significantly inhibits compulsive cocaine seeking, providing a...
In the field of substance use prevention and treatment choosing the correct terminology can be tricky, especially if we want to avoid contributing to stigmatised perceptions of people battling with substance use disorders.
‘Abuse’, ‘abuser...
Especially due to its large sample size and incorporation into the CPS survey, the TUS provides a unique opportunity for tracking long-term trends in tobacco use, cessation attempts, and tobacco-related policies; evaluation of tobacco...
Although progress in science has driven advances in addiction medicine, this subject has not been adequately taught to medical trainees and physicians. As a result, there has been poor integration of evidence-based...
Second cell of the Drug Treatment Matrix explores key studies on the impact of the practitioner on reducing harms associated with illegal drug use, in which trust emerges as a fundamental ingredient. Reconceptualise needle exchanges as safe...
The neurobiological mechanisms that underlie the resistance of drug cue associations to extinction in addiction remain unknown. Fear extinction critically depends on the ventromedial prefrontal cortex (VMPFC). Here, we tested if...
Background: Multimorbidity, the co-existence of two or more (2+) long-term conditions in an individual, is common among problem drug abusers.
Objective: To delineate the patterns, multimorbidity prevalence, and disease severity...
Methadone maintenance therapy (MMT) is a mainstay for treating opioid use disorder and preventing and managing HIV among people who inject drugs (PWID). While previous research suggested low dosing of methadone and...
Persons who use opioids have a high risk of overdose and associated mortality. In Vietnam, little is known about the characteristics of this population and the persons who are witness to those overdoses. One approach...
