Objective To identify and describe evidence on brief emergency department (ED)-delivered behavioural and care process interventions among patients presenting with suicide attempt or acute ideation, substance overdose or psychosis...
We evaluated the impact of a telemedicine bridge clinic on treatment outcomes and cost for patients with opioid use disorder. Telemedicine bridge clinics deliver low-barrier rapid assessment of patients with opioid use...
Ibogaine (IBO) is an atypical psychedelic with a complex mechanism of action. To date, the mechanisms that may underlie its anti-addictive effects are still not defined. This study aims to identify changes in gene expression...
Opioid use disorder (OUD) in the United States has surged, with an estimated 2.5 million needing treatment. The aim of this article is to provide a clinical overview of the key pharmacological and behavioral treatments...
Stimulants are a class of drugs that act on the central nervous system, increasing alertness, energy, and attention while elevating mood. They achieve these effects by enhancing the activity of neurotransmitters such as dopamine and...
Background: Over the past decade, drug-related overdoses have seen a significant rise both in North America and globally. The COVID-19 pandemic has further emphasised the urgent need for safer supply programs to replace unregulated...
Specific patterns of substance use have been found to correlate with an elevated risk of suicidal thoughts, attempts, and mortality by suicide. However, this relationship is multifaceted and influenced by various intersecting factors...
An app that keeps track of how much a person is drinking could help reduce their alcohol intake by around two units a week – equivalent to a medium glass of wine, scientists say.
Constituting the fourth part of the World Drug Report 2022, this booklet focuses on the market dynamics of various stimulants – cocaine, amphetamines and “ecstasy” – and of NPS.
It contains an analysis of the global market for cocaine...
Methadone coverage is poor in many countries due in part to methadone induction being possible only in specialized care (SC). This multicenter pragmatic trial compared the effectiveness of methadone treatment between...
