This refers to the physical and emotional reactions that occur when a person reduces or stops using a substance their body has become dependent on. These effects often begin within 4 to 72 hours after the last dose and can include watery eyes, yawning, loss of appetite, panic, insomnia, vomiting, shaking, irritability, and jitteriness.
While not typically life-threatening, withdrawal can be painful and distressing, and medical support is often recommended to ease discomfort and prevent complications.
Sources: ProjectKnow