Supply and market disruption refers to coordinated strategies aimed at reducing the production, trafficking, distribution, and availability of illicit substances. These strategies often involve law enforcement, regulatory controls, border management, and financial investigations designed to disrupt drug trafficking networks and weaken illicit drug markets. By targeting supply chains and market dynamics, these efforts aim to reduce the availability of drugs, increase the risks and costs associated with illegal production and distribution, and contribute to broader efforts to reduce substance-related harms. Effective supply and market disruption typically operates alongside public health, prevention, treatment, and recovery responses as part of a comprehensive approach to substance use.
Supply & Market Disruption
Drug production and precursors — EUDA ongoing activities
The European Union Drugs Agency (EUDA) continues to monitor illicit drug production and precursor chemicals across Europe to improve understanding of how drug markets are evolving. Production within the European Union is primarily focused...
2025 National Drug Threat Assessment (NDTA) - Drug Enforcement Administration (DEA)
The U.S. Drug Enforcement Administration (DEA) has released its 2025 National Drug Threat Assessment (NDTA), providing an overview of the threats posed by illicit drugs and the transnational criminal organizations involved in their...
UN Toolkit on Synthetic Drugs
The UN Toolkit on Synthetic Drugs is a practical online resource coordinated by UNODC that brings together tools, guidance, and operational resources from across the UN system to support responses to the global synthetic drug problem...
New UNODC Toolkit Module on Security Document Examination: Launching event
UNODC has launched a new Security Document Examination module within the UN Toolkit on Synthetic Drugs to help law enforcement, border control, and forensic professionals detect and respond to document fraud linked to synthetic drug trafficking.
NEW Security Document Examination module in the UN Toolkit on Synthetic Drugs
UNODC has launched a new Security Document Examination module within the UN Toolkit on Synthetic Drugs, developed in collaboration with the UNODC Laboratory and Scientific Services. The module aims to help law enforcement, border control...
UNODC Current NPS Threats
The UNODC Early Warning Advisory highlights a continued global expansion of new psychoactive substances (NPS), with nearly 1,400 substances reported worldwide. In 2024 alone, a record number of substances were identified, including over 100...
EU controls nine drug precursors following first EUDA assessments
The European Commission has introduced new controls on nine high-risk chemical precursors used in illicit drug production under Delegated Regulation (EU) 2026/314. Most of these substances are linked to synthetic cathinones, while one is...
Leveraging National Surveillance Networks for Local Action and Collective Impact
Featuring: Dr. Samantha King, CCSA Research and Policy Analyst
Ketamine in Europe
Objective: This webinar aims to provide insights into the European ketamine market and will expand on health-related harms caused by non-medical ketamine use.
2026 National Drug Control Strategy - The White House
The 2026 National Drug Control Strategy outlines a comprehensive roadmap to reduce illicit drug use and protect communities across the United States. It prioritizes stopping the flow of drugs and precursor chemicals at all borders through...