polysubstance use

UNODC Current NPS Threats

Report

12 December 2025

The UNODC Early Warning Advisory highlights a continued global expansion of new psychoactive substances (NPS), with nearly 1,400 substances reported worldwide. In 2024 alone, a record number of substances were identified, including over 100...

From Parenting to Polysubstance Use: The Role of Attachment and Psychosocial Mechanisms in Addiction Vulnerability

Leaflet, Infographic, Fact sheet, Poster

19 November 2025

Background: Polysubstance use disorder (PSUD) in adolescents and young adults is often rooted in early family dynamics. Baumrind’s typology—later extended by Maccoby & Martin and the integrative model of Darling & Steinberg—offers a...

Inflammatory Markers (Lymphocyte-Related Ratio) and Polysubstance Use Severity: Insights from a Bali Mental Hospital Rehabilitation Study

Leaflet, Infographic, Fact sheet, Poster

6 November 2025

Background: Substance use disorders (SUDs) are a global health issue, contributing significantly to morbidity and mortality. Chronic polysubstance use exacerbates systemic inflammation, which is associated with addiction severity...

Understanding the risks of mixing drugs

Video and audio recordings

17 February 2022

February 17, 2022 Mixing drugs, also known as polysubstance use, occurs when two or more drugs are taken together or within a short time period, intentionally or unintentionally. Even if someone has mixed drugs before, or mixes drugs often...

Trends in Cannabis Polysubstance Use During Early Pregnancy Among Patients in a Large Health Care System in Northern California

Scientific article

6 June 2022

Abstract Importance Rates of prenatal cannabis use are increasing alongside perceptions that cannabis is a harmless therapeutic for pregnancy-related ailments, while rates of prenatal use of alcohol and tobacco are decreasing. It is...

Pattern and Determinants of Alcohol and Tobacco Co-Use and its Relationship with Smoking Cessation in Hong Kong

Scientific article

ABSTRACT Introduction: Alcohol and tobacco are often used together. Studies have shown that some biological factors contribute to the concurrent use of alcohol and nicotine. There have been comparatively few studies that document the...

Polysubstance among stimulant users: Course, complications and the clinical pictures

Video and audio recordings

Substance Use Patterns and Health Profiles among US Adults who Use Opioids, Methamphetamine, or Both, 2015-2018

Scientific article

2 July 2020

Abstract Background Methamphetamine use, with and without opioids, has increased substantially, but little is known about the sociodemographic characteristics, substance use patterns, or health profiles of individuals who use...

The Readiness Ruler as a Measure of Readiness to Change Poly-Drug Use in Drug Abusers

Scientific article

Abstract Readiness to change is a crucial issue in the treatment of substance use disorders. Experiences with methadone maintenance treatment (MMT) has shown that continuous drug and alcohol use with all its consequences characterize most...

Alcohol Treatment in Ireland 2011 to 2017

Book

20 March 2019

The Health Resource Board has published its latest bulletin and infographic describing the trends in treated problem alcohol use between 2011 to 2017.